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Based in Porto, Portugal where she treats many hundred sufferers with the condition, Dr. Coelho is an renowned professional in ATTR internationally. She added, ‘The pre-medical data with ALN-TTR01 obtained to time are promising, especially recent results displaying regression of pathogenic TTR cells deposition in the mouse transgenic model. By all accounts, I am worked up about the translation of this new agent into scientific trials as there are currently few options for patients suffering from this disease.’ ALN-TTR01 is in clinical advancement using stable nucleic acid-lipid contaminants delivery technology developed in collaboration with Tekmira Pharmaceuticals Company.. Alnylam Pharmaceuticals initiates dosing in Stage I human clinical study with ALN-TTR01 Alnylam Pharmaceuticals, Inc.