Aastrom Biosciences responds to article regarding contaminated stem cell lines Aastrom Biosciences responded today to the publication in the Sunday online edition of Character Medicine of findings by California researchers that indicate that certain lines of human embryonic stem cells have been contaminated by using mice feeder cells generic priligy . The Company has received numerous inquiries regarding these results and their impact on Aastrom Biosciences. Aastrom does not use embryonic stem cells, nor will it use mouse-derived feeder cells to support stem cell growth, the two major topics of yesterday’s content. This is a critical reality that differentiates our Cells Restoration Cells from other stem cell approaches presently in advancement.
Results were provided at the annual American Society of Nephrology conference in Denver, Colorado. Crucial findings from the 8-week study of three dosages of atrasentan vs. Placebo were: Atrasentan considerably reduced urine albumin-to-creatinine ratio in the 0.75 mg and 1.75 mg groups vs. Placebo . The 0.25 mg dose acquired no significant effect Reduction from baseline to final UACR was 21 percent, 42 percent, and 34 percent in the 0.25 mg, 0.75 mg and 1.75 mg groups vs. 11 percent in placebo A statistically significant proportion of subjects achieved >40 percent reduction in UACR from baseline in the 0.75 mg group vs. Placebo . The proportion of sufferers in the 0.25 mg and 1.75 mg groups did not reach statistical significance. Peripheral edema was the most common adverse event ‘Several large scientific trials with RAS inhibitors have demonstrated that reductions in albuminuria are connected with a delay in the progression of diabetic nephropathy,’ said Donald E.