By considerably the earliest & most common genetic alteration in melanoma is usually a mutation in an oncogene – – a gene that may cause regular cells to become tumor cells – – called BRAF. For this study, scientists produced a mouse that allowed them to change on that oncogene in melanocytes. The study team discovered that the benign lesions observed in a mouse expressing the gene are very like the benign sun-induced moles that often develop in humans and which also contain BRAF mutations. Benign sun-induced moles never progress to malignancy generally, but such lesions certainly are a potential precursor to tumor.Banahan III, PhD, and Donna S. West-Strum, PhD, for Measuring Pharmacy Functionality in the region of Medication Adherence: Addressing the problem of Risk Adjustment.. 8 quotes from a cancer surgeon that may set your hair on fire His name is Marty Makary. He’s a cancer doctor and researcher at the Johns Hopkins College of Medication and the institution of Public Wellness. Propublica’s Marshall Allen interviewed him about patient harm, in conjunction with a continuing propublica investigation. Keep in mind that these quotations are coming from a mainstream doctor who’s inside the system and who believes in the machine.