Seery says that prior attempts to comprehend the persistence, refractoriness and disability associated with CBP possess underscored the importance of psychosocial variables and demonstrated a link between CBP and lifetime contact with adverse events. Previous research suggests that contact with adverse life events correlates with greater CBP severity, he says. This implies that the perfect situation will be one in which individuals have not been exposed to any adverse life time events. It seems, however, that the relationship between adversity and chronic pain isn’t so simple, for the reason that experiencing some prior adversity is in fact most beneficial, Seery says..In ongoing studies, the Penn State researchers also have shown AAV2 can destroy cells derived from prostate cancer, methoselioma, squamous cell carcinoma, and melanoma. A 4th line of breast cancers cells – representing the most intense form of the disease – was also studied in a mouse breast tumor model, followed by treatment with AAV2. Preliminary results show the destruction of the tumors in the mice, and researchers shall report the findings of these mouse studies soon.. M. Arfan Ikram, M.D., Sudha Seshadri, M.D., Joshua C.