Monday experts said.

Few can doubt there is a particular issue in the U.K., wrote Sir Ian Gilmore of the University of Southampton and co-workers in a commentary published online Mon in the journal, Lancet. Based on current numbers and trends, however, they warned there may be as much as 8,900 deaths every year. That would mean up to 250,000 people could be killed by alcohol over the next 20 years. If the national government takes measures to lessen alcohol consumption, the analysis predicts there would be 2, 500 alcohol related deaths every full year by 2019.Jacobson, M.D., Stuart C. Gordon, M.D., Kris V. Kowdley, M.D., Eric M. Yoshida, M.D., Maribel Rodriguez-Torres, M.D., Mark S. Sulkowski, M.D., Mitchell L. Shiffman, M.D., Eric Lawitz, M.D., Gregory Everson, M.D., Michael Bennett, M.D., Eugene Schiff, M.D., M. Tarek Al-Assi, M.D., G. Mani Subramanian, M.D., Ph.D., Di An, Ph.D., Ming Lin, Ph.D., John McNally, Ph.D., Diana Brainard, M.D., William T. Symonds, Pharm.D., John G. McHutchison, M.D., Keyur Patel, M.D., Jordan Feld, M.D., M.P.H., Stephen Pianko, M.D., Ph.D., and David R. Nelson, M.D.1-4 However, a considerable proportion of sufferers with HCV infection remain untreated due to complete or relative contraindications to interferon therapy, such as for example hepatic decompensation, autoimmune disease, and psychiatric illness.5 Furthermore, interferon causes a variety of constitutional symptoms or hematologic abnormalities that may necessitate discontinuation of therapy in a sigificant number of patients.6 Some patients decide against interferon therapy for a variety of reasons, including aversion to anxiety and injections about the adverse events connected with treatment.